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- Citation
- Journal of the American Heart Association 2020 Apr 24
- Date
- April 24, 2020
- Link
- View Link
Abstract Background We investigated the effects of insulin, glucagon‐like peptide‐1 receptor agonists (GLP‐1RA), sodium‐glucose cotransporter‐2 inhibitors (SGLT‐2i), and their combination on vascular and cardiac function of […]- Citation
- J Clin Med. 2019 Jul 5;8(7):983.
- Date
- July 5, 2019
- Link
- View Link
Abstract Background: Poor glycaemic control affects myocardial function. We investigated changes in endothelial function and left ventricular (LV) myocardial deformation in poorly controlled type 2 diabetics before […]- Citation
- Journal of Clinical Monitoring and Computing (2021)
- Date
- February 3, 2021
- Link
- View Link
Abstract The endothelium and the glycocalyx play a pivotal role in regulating microvascular function and perfusion in health and critical illness. It is unknown today, whether […]- Citation
- Diabetologia. 2010 Dec;53(12):2646-55
- Date
- September 25, 2010
- Link
- View Link
Abstract Aims/hypothesis: Endothelial glycocalyx perturbation contributes to increased vascular permeability. In the present study we set out to evaluate whether: (1) glycocalyx is perturbed in individuals with […]- Citation
- Scientific Reports (Nature Publisher Group); London Vol. 11, Iss. 1, (2021)
- Date
- February 4, 2021
- Link
- View Link
Prematurity predisposes to cardiovascular disease; however the underlying mechanisms remain elusive. Disturbance of the endothelial glycocalyx (EG), an important regulator of vessel function, is thought to […]- Citation
- JHypertens. 2015 Jun;33 Suppl 1
- Date
- June 1, 2015
- Link
- View Link
Abstract Objective: Abnormal microvascular structure and function have been related to hypertension. Increasing evidence links Na+ to microvascular changes. Whether a chronic dietary Na+ load or […]- Citation
- Clin Hemorheol Microcirc. 2018 Nov 2. doi: 10.3233/CH-189907. [Epub ahead of print]
- Date
- November 2, 2018
- Link
- View Link
Abstract Background and objective: The endothelial glycocalyx (EG) is fragile and sensitive to damage such as exposure to hypernatremia. Our aim was to describe the influence of […]- Citation
- J Am Heart Assoc. 2019 Feb 19;8(4):e010647.
- Date
- February 19, 2019
- Link
- View Link
Abstract Background The endothelial glycocalyx is a vasoprotective barrier between the blood and endothelium. We hypothesized that glycocalyx degradation is present in preeclampsia, a pregnancy-specific hypertensive […]- Citation
- Int J Cardiol. 2017 Apr 15;233:105-112.
- Date
- April 15, 2017
- Link
- View Link
Abstract Background: First-degree relatives of type-2 diabetes patients (FDR) present insulin resistance. We investigated whether FDR and dysglycaemic subjects demonstrate abnormal endothelial glycocalyx and LV deformation during […]- Citation
- Clin Rheumatol. 2021 Jan 7.
- Date
- January 7, 2021
- Link
- View Link
Abstract In this study, we examine sublingual videomicroscopy and nailfold videocapillaroscopy (NVC) features in systemic sclerosis (SSc) patients presenting for routine care. Consented participants met classification […]- Citation
- Wiley Online Library, 2018 December
- Date
- December 24, 2018
- Link
- View Link
Summary The vascular endothelial surface is coated by the glycocalyx, a ubiquitous gel-like layer composed of a membrane-binding domain that contains proteoglycans, glycosaminoglycan side-chains, and plasma […]- Citation
- PLoS One. 2014 May 9;9(5):e96477
- Date
- May 9, 2014
- Link
- View Link
Abstract Changes in endothelial glycocalyx are one of the earliest changes in development of cardiovascular disease. The endothelial glycocalyx is both an important biological modifier of […]
