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- Citation
- PLoS One. 2014 May 9;9(5):e96477
- Date
- May 9, 2014
- Link
- View Link
Abstract Changes in endothelial glycocalyx are one of the earliest changes in development of cardiovascular disease. The endothelial glycocalyx is both an important biological modifier of […]- Citation
- Scientific Reports (Nature Publisher Group); London Vol. 11, Iss. 1, (2021)
- Date
- February 4, 2021
- Link
- View Link
Prematurity predisposes to cardiovascular disease; however the underlying mechanisms remain elusive. Disturbance of the endothelial glycocalyx (EG), an important regulator of vessel function, is thought to […]- Citation
- J Clin Hypertens (Greenwich). 2018 Nov;20(11):1615-1623.
- Date
- October 13, 2018
- Link
- View Link
Abstract Endothelial dysfunction indicates target organ damage in hypertensive patients. The integrity of endothelial glycocalyx (EG) plays a vital role in vascular permeability, inflammation and elasticity, […]- Citation
- Journal of Cardiovascular Translational Research 28 Oct 2021
- Date
- October 28, 2021
- Link
- View Link
Abstract We investigated whether disturbance of glycocalyx integrity is related with increased cardiovascular risk. In 600 healthy subjects, we measured perfused boundary region (PBR), a marker […]- Citation
- Microcirculation. 2018 May;25(4):e12454. doi: 10.1111/micc.12454.
- Date
- December 25, 2017
- Link
- View Link
Abstract Objective: PBR characterizes penetration of red blood cells inside glycocalyx and its thickness can have profound impact on microcirculation and other vascular parameters. The goal of […]- Citation
- J Mol Cell Cardiol. 2019 Feb;127:74-82. doi: 10.1016/j.yjmcc.2018.11.014. Epub 2018 Nov 29.
- Date
- November 29, 2018
- Link
- View Link
Abstract Age-related vascular dysfunction in large elastic and resistance arteries is associated with reductions in microvascular perfusion and elevations in blood pressure. Recent evidence indicates that […]- Citation
- Eur J Cardiovasc PrevRehabil. 2011 Dec;18(6):775-89
- Date
- December 1, 2011
- Link
- View Link
Abstract The endothelium holds a pivotal role in cardiovascular health and disease. Assessment of its function was until recently limited to experimental designs due to its […]Microvascular Alterations During Cardiac Surgery Using a Heparin or Phosphorylcholine-Coated Circuit
- Citation
- J Cardiothorac Vasc Anesth. 2020 Apr;34(4):912-919
- Date
- April 1, 2020
- Link
- View Link
Abstract Objective: Heparin biocompatible coating frequently is used to reduce inflammation and blood coagulation during cardiopulmonary bypass (CPB) in cardiac surgery. Whether heparin coating is protective or […]- Citation
- Obesity: A Research Journal. 2 August 2021
- Date
- August 2, 2021
- Link
- View Link
Abstract Objective This study aimed to investigate microvascular differences in individuals with obesity at risk for developing cardiovascular disease. Methods In this cross-sectional Netherlands Epidemiology of […]- Citation
- J Thorac Cardiovasc Surg. 2015 Dec;150(6):1474-81.
- Date
- August 24, 2015
- Link
- View Link
Abstract Objective: Perturbation of the endothelial glycocalyx is discussed in the pathogenesis of complications related to cardiopulmonary bypass. We evaluated the effects of cardiopulmonary bypass on the […]- Citation
- J Clin Hypertens (Greenwich). 2020 Oct;22(10):1827-1834.
- Date
- August 13, 2020
- Link
- View Link
Abstract Smoking, a well-recognized major cardiovascular (CV) risk factor, impairs endothelial function and increases aortic stiffness which indicates subclinical organ damage in hypertensive patients. Loss of […]- Citation
- Microcirculation. 2016 Jan;23(1):69-74.
- Date
- January 1, 2016
- Link
- View Link
Abstract Objectives: Endothelial glycocalyx injury causes microcirculatory perfusion disturbances in experimental studies, but the relevance in a clinical setting remains unknown. We investigated whether glycocalyx dimensions are […]