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- Citation
- Am J Physiol Renal Physiol. 2010 Nov;299(5):F1134-40
- Date
- September 1, 2010
- Link
- View Link
Abstract Increased understanding of the pathophysiology of ischemic acute kidney injury in renal transplantation may lead to novel therapies that improve early graft function. Therefore, we […]- Citation
- Clin J Am SocNephrol. 2014 Apr;9(4):698-704
- Date
- January 23, 2014
- Link
- View Link
Abstract Background and objectives: ESRD is accompanied by endothelial dysfunction. Because the endothelial glycocalyx (endothelial surface layer) governs interactions between flowing blood and the vessel wall, perturbation […]- Citation
- J Am SocNephrol. 2012 Nov;23(11):1900-8
- Date
- October 18, 2012
- Link
- View Link
Abstract Damage to the endothelial glycocalyx, which helps maintain vascular homeostasis, heightens the sensitivity of the vasculature to atherogenic stimuli. Patients with renal failure have endothelial […]Effects of ultrapure hemodialysis and low molecular weight heparin on the endothelial surface layer.
- Citation
- Blood Purif. 2014;38(3-4):203-10
- Date
- December 16, 2014
- Link
- View Link
Abstract Background: Chronic kidney disease patients show changes in the endothelial surface layer (ESL). Whether hemodialysis (HD) itself or low molecular weight heparins (LMWH) induce ESL alterations […]- Citation
- PLoS One. 2017 Aug 22;12(8):e0183281.
- Date
- August 22, 2017
- Link
- View Link
Abstract Background: Haemodialysis (HD) patients are predisposed to dysregulated fluid balance leading to extracellular water (ECW) expansion. Fluid overload has been closely linked with outcome in these […]- Citation
- Kidney Blood Press Res. 2017;42(5):905-918.
- Date
- November 16, 2017
- Link
- View Link
Abstract Background: Cardiovascular disease is a major contributor to the poor outcomes observed in hemodialysis. We investigated the relationship between hemodialysis intensity and vascular parameters in high-dose […]- Citation
- Molecular Genetics and Genomics 01 February 2022
- Date
- February 1, 2022
- Link
- View Link
Abstract In this study, the effect of heterozygous germline mutations in the heparan sulfate (HS) glycosaminoglycan chain co-polymerases EXT1 and EXT2 on glomerular barrier function and […]- Citation
- American Journal of Nephrology 08 March 2022
- Date
- March 8, 2022
- Link
- View Link
Abstract Background: Mitochondrial, lysosomal, and peroxisomal dysfunction; defective autophagy; mitophagy; and pexophagy, as well as the loss of glycocalyx integrity are known contributors to initiation and progression […]
